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Pharmaceutical Chemistry III Physical Chemistry

B Pharmacy 2nd Year Annual

BPH – 211

Time: Three Hours                                                                         M. Marks : 80

Note: Attempt any five questions. All questions carry equal marks.

  1. (A) What is Equilibrium Constant? How it is affected by temperature, pressure and volume?
    (B) How physiosorption differs from chemisorption? Elaborate on the use of BET equation in surface area determination.
  2. (A) Discuss the isothermal process in an ideal gas.
    (B) What are the limitations of the first law of thermodynamics?
  3. (A) What is Lewis fugacity rule? Express the relation between Kp and Kc?
    (B) Discuss the applications of Clapeyron-Clausius equation.
  4. (A) How freezing point of a solvent is affected by addition of a non-volatile solute? Explain with the help of heat plot between vapour pressure and temperature.
    (B) Discuss phase diagram for two component system.
  5. (A) Give a detailed account on Carnot Cycle.
    (B) Calculate the boiling point of a solution of 0.5 g of a solute (M.W. 128) in 100g of water. (Boiling point and Kb of pure water are 100° C and 5° C/mole/1000g, respectively)
  6. Write short notes on:
    (A) Geometry and symmetry of crystals
    (B) Partition coefficient and its importance
    (C) Collision theory of Kinetics
    (D) Debye-Huckel Theory
  7. (A) What is a second order reaction? Discuss with a suitable example.
    (B) What is activation energy? How catalysis lowers the energy barrier?
  8. Elaborate on various properties of the liquids. How these are useful in structural elucidation?
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