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PHARMACEUTICAL CHEMISTRY-I paper 2010

Roll No.....................                                                                                            May, 2010/1001
(B. Pharmacy 1st Year-Annual)
PHARMACEUTICAL CHEMISTRY-I
(Inorganic Chemistry) BPH-111
Time: Three Hours                                                                                                 M. Marks: 80

Note: Attempt any five questions. All questions carry equal marks.

Q.1    What are limit tests? Discuss in detail the chemistry, procedure and apparatus used in the limit test for arsenic.

Q.2    What are antacids? What is the basis of combination antacid formulations? Discuss in detail, compound from the category of Aluminium and Magnesium antacids.

Q.3    Discuss in detail electrolyte combination therapy. What are the pharmaceutical substances used in this category? Explain highlighting the chemistry of important substances.

Q.4    Give the methods of preparation, uses, sources of impuritie, tests for purity and identity of the following:

(a) Potassium Permanganate

(b) Ammonium Carbonate

(c) Magnesium Sulphate

(d) Potassium iodide

Q.5    Give an account of the inorganic products used to manage heavy metal and cyanide poisoning giving their preparation method and identification tests.

Q.6    What is the pharmaceutical importance of antioxidants? Give an account of chemistry and purity aspects of the various compounds in this category.

Q.7    Write short notes on:

(a) Desensitizing agents in dentifrices

(b) Topical protectives

Q.8    Discuss the various theoretical aspects of radioactivity. Comment on the therapeutic diagnostic and research applications of radioisotopes.

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