BPH-405: PHARMACEUTICS-XI
(PHARMACEUTICAL PACKAGING TECHNOLOGY)
THEORY
Max. Marks: 80 Total Hours: 50 (2hrs/week)
Note: Examiner to set eight questions and the candidates are required to attempt any five.
- Introduction: Definition and objectives of packaging, hazards encountered by the package, selection of a suitable package, objectives, selection and different types of closures, child resistant packaging, tamper proof packaging, and cushioning design. (6)
- Packaging materials: Detailed study with regard to materials employed for packaging of pharmaceuticals with main emphasis on glass, plastics, metals rubber, paper board, corrugated boards. Evaluation of various packaging materials. (7)
- Films for Flexible Packages: Ideal characteristics, formulation and different types of films for flexible package, production of single layer and oriented films, production of laminates, evaluation of films. (5)
- Strip Packing: Advantages of Strip Packing, Strip packaging machinery, strip package design and evaluation of strip package. (4)
- Blister Packaging: Advantages of Blister packing, Blister packing materials, blister packing machinery, blister package design and evaluation of blister package. (4)
- Pouch packaging: Advantages of Pouch packing, pouch packing machinery, types of pouch package, pouch package design and evaluation of pouch package. (4)
- Liquid Formulation Packaging: Factors influencing selection of liquid filling machinery. Balanced and unbalanced constant level filling, volumetric, gravimetric, level sensing, time fill, peristaltic and overflow liquid filling machinery. (5)
- Dry products Filling machinery: Factors influencing selection of solid filling machinery. Augers, vibrating feeders, gravity flow systems, belt feeders, screw feeders, cascade filling systems, vacuum filling systems, weighing systems. (5)
- Sterile Product Packaging: Various types of containers used for sterile products like ampoules, vials, bottles for I.V. fluid, etc. Types of closures used for the sterile products. Sterile product filling and sealing machinery i.e. ampoule filling and sealing machine. Evaluation of the sterile product packages. (5)
- Labeling: Objectives, legal requirements, packaging inserts, bar code, bar code symbologies, types of labels and labeling machinery. (5)
- Wiley Encyclopedia of Packaging Technology. Aaron L Brody and Kenneth S Marsh, John Wiley and Sons, Inc.
- Encyclopedia of Pharmaceutical Technology, James Swarbrick, James C. Boylan, Marcel Dekker, Inc.
- Pharmacy Law and Practice. Jonathan Merrills and Jonathan Fisher. Blackwell Science.
- What is packaging design. Giles Calvier. Rotovision SA.
- International Pharmaceutical Product Registration: Aspects of Quality, Safety and Efficacy. Cartwright, A. C., Matthews, Brian. Taylor & Francis Routledge.