BPH-314: PHARMACOLOGY –II
PRACTICAL
Max. Marks: 80 Total Hours: 75 (3hrs/week)
- Introduction to Experimental Pharmacology.
- Preparation of different solutions for experiments.
- Common Laboratory animals and their maintenance.
- Study of commonly used instruments in experimental pharmacology.
- Procedures for rendering animals unconscious – stunning of rodents, pithing of frogs, chemical anaesthesia.
- Experiments on intact preparations:
i. Study of different routes of administration of drugs in mice / rats. To study the effect of hepatic microsomal enzyme inhibitors and induction on the
ii. pentobarbitone/hexobarbitone/thiopental sodium sleeping time in mice.
Experiments on Central Nervous System:
i. Recording of spontaneous motor activity, stereotypy, analgesia, anticonvulsant activity and muscle relaxant activity of drugs using simple experiments.
ii. Effects of autonomic drugs on rabbit’s eye.
Pharmacology of Cardiovascular System:
i. To study the inotropic and chronotropic effects of drugs on isolated frog heart.
ii. To study the effects of drugs on normal and hypo dynamic frog heart.
NOTE: ANY OTHER EXPERIMENTS (S) MAY BE INCLUDED IN SUPPORT OF THE THEORETICAL ASPECTS OF THE COURSE.
Books Recommended (Latest editions)
- Essentials of Medical Pharmacology, K.D.Tripathy, JAYPEE.
- Pharmacology & Parmacotherapeutics, Satoshkar & Bhandarkar, Popular Publication.
- Pharmacology, Prasun Kumar Das, S.K.Bhattacharya, Elsevier.
- The Pharmacological Basis of Therapeutics, Goodman & Gilman, Mc Graw Hill.
- Text book of Pharmacology, S.D. Sethi, BI Churchill Livinstone.
- Pharmacology, Rang, Dale and Ritter, Churchill Living Stone.
- Basic & Clinical Pharmacology, B.G.Katzung, Lange.
- Pharmacology, Mary J, Mycer, Richard A, Lippincott William & Willans.
Click here for PHARMACOLOGY –II Theory Syllabus