BPH-306: PHARMACOLOGY –II
THEORY
Max. Marks: 80 Total Hours: 75 (3hrs/week)
Note: Examiner to set eight questions and the candidates are required to attempt any five.
1) General pharmacology:
a. Introduction to pharmacology, sources of drugs, dosage forms and routes of administration, mechanism of action, combined effect of drugs, factors modifying drug action, tolerance and dependence, pharmacogenetics.2) Pharmacology of autonomic nervous system:
b. Absorption, distribution, metabolism and excretion of drugs, principles of basic and clinical pharmacokinetics, adverse drug reactions and treatment of poisoning, ADME drug reactions, bioassay of drugs and biological standardization, discovery and development of new drugs.
a. Neurohumoral transmission (autonomic and somatic)3) Pharmacology of Central Nervous System:
b. Parasympathomimetics, Parasympatholytics, Sympathomimetics, Sympatholytics, Ganglion blocking and Stimulating agents
c. Neuromuscular blocking agents.
d. Local anaesthetic agents.
a. Neurohumoral transmission in the C.N.S.4) Pharmacology of Cardiovascular system:
b. General anaesthetics
c. Alcohols and Disulfiram
d. Sedative and hypnotics
e. Anti-anxiety agents and centrally acting muscle relaxants
f. Psychopharmacological agents (Anti-psychotic, antidepressants, antimaniacs and hallucinogens)
g. Anti-epileptic drugs
h. Anti-parkinsonian drugs
i. Analgesics, antipyretics and anti-inflammatory agents
j. Narcotic analgesics and antagonists.
k. CNS stimulants
a. Digitalis and cardiac glycosides5) Drugs acting on the Haematopoietic system:
b. Anti-hypertensive drugs
c. Anti-anginal and vasodilator drugs
d. Anti-arrhythmic drugs.
e. Anti-hyperlipidemic drugs
f. Drugs used in therapy of shock
a. Haemitinics6) Drugs acting on the urinary system:
b. Anticoagulants, vitamin K and haemostatic agents
c. Fibrinolytic and Anti-platelet drugs
d. Blood and plasma volume expanders
a. Fluid and electrolytic balance7) Autocoids:
b. Diuretics
a. Histamine, 5-HT and their antagonists8) Drugs acting on the respiratory system:
b. Prostaglandins, thromboxane and Leukotrienes
c. Pentagastrin, cholecystokinins, angiotensin, bradykinin and substance P.
a. Anti-asthmatic drugs including bronchodilators
b. Anti-tussive and Expectorants
c. Respiratory stimulants
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