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PHARMACOLOGY –II Theory Syllabus

BPH-306: PHARMACOLOGY –II
THEORY


Max. Marks: 80                                                                                     Total Hours: 75 (3hrs/week)

Note: Examiner to set eight questions and the candidates are required to attempt any five.
1) General pharmacology:

a. Introduction to pharmacology, sources of drugs, dosage forms and routes of administration, mechanism of action, combined effect of drugs, factors modifying drug action, tolerance and dependence, pharmacogenetics.

b. Absorption, distribution, metabolism and excretion of drugs, principles of basic and clinical pharmacokinetics, adverse drug reactions and treatment of poisoning, ADME drug reactions, bioassay of drugs and biological standardization, discovery and development of new drugs.
2) Pharmacology of autonomic nervous system:
a. Neurohumoral transmission (autonomic and somatic)
b. Parasympathomimetics, Parasympatholytics, Sympathomimetics, Sympatholytics, Ganglion blocking and Stimulating agents
c. Neuromuscular blocking agents.
d. Local anaesthetic agents.
3) Pharmacology of Central Nervous System:
a. Neurohumoral transmission in the C.N.S.
b. General anaesthetics
c. Alcohols and Disulfiram
d. Sedative and hypnotics
e. Anti-anxiety agents and centrally acting muscle relaxants
f. Psychopharmacological agents (Anti-psychotic, antidepressants, antimaniacs and hallucinogens)
g. Anti-epileptic drugs
h. Anti-parkinsonian drugs
i. Analgesics, antipyretics and anti-inflammatory agents
j. Narcotic analgesics and antagonists.
k. CNS stimulants
4) Pharmacology of Cardiovascular system:
a. Digitalis and cardiac glycosides
b. Anti-hypertensive drugs
c. Anti-anginal and vasodilator drugs
d. Anti-arrhythmic drugs.
e. Anti-hyperlipidemic drugs
f. Drugs used in therapy of shock
5) Drugs acting on the Haematopoietic system:
a. Haemitinics
b. Anticoagulants, vitamin K and haemostatic agents
c. Fibrinolytic and Anti-platelet drugs
d. Blood and plasma volume expanders
6) Drugs acting on the urinary system:
a. Fluid and electrolytic balance
b. Diuretics
7) Autocoids:
a. Histamine, 5-HT and their antagonists
b. Prostaglandins, thromboxane and Leukotrienes
c. Pentagastrin, cholecystokinins, angiotensin, bradykinin and substance P.
8) Drugs acting on the respiratory system:
a. Anti-asthmatic drugs including bronchodilators
b. Anti-tussive and Expectorants
c. Respiratory stimulants

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