(B. Pharmacy 1st Year-Annual)
PHARMACEUTICAL CHEMISTRY-II
(Organic Chemistry) BPH-112
Time: Three Hours M. Marks: 80PHARMACEUTICAL CHEMISTRY-II
(Organic Chemistry) BPH-112
Note: Attempt any five questions. All questions carry equal marks
Q.1 Discuss any four of the following:
(a) Bonding and antibonding orbitals
(b) Geometric Isomerism
(c) Inner and outer orbital complexes
(d) Axial and equatorial bonds
(e) Z & E nomenclature
Q.2 Define Configuration. Discuss specification of configuration giving sequence modifications.
Q.3 Define racemic modifications. Discuss methods of resolution of racemic modifications.
Q.4 Discuss any two of the following in detail:
(a) Polarity of bonds and molecules
(b) Electro negativity
(c) Conformational isomerism
Q.5 Discuss any two of the following in detail:
(a) Aceto-acetic Ester synthesis of Ketones
(b) Benzoin Condensation
(c) Preparation and reactions of Grignard reagent
Q.6 Write notes on any two of the following:
(a) Vander Walls forces
(b) Optical purity
(c) Tautomerism
(d) Inductive and field effects
(e) Lone pair of Electrons
Q.7 Discuss any four of the following:
(a) Halogenation of Alkanes
(b) Reimer-Tiemann Reaction
(c) Cannizzaro reaction
(d) Williamson’s synthesis
(e) Sulfonation of Benzene
Q.8 Give a detailed account of any two of the following:
(a) Electrocyclic Reactions
(b) Neighboring group effect
(c) Stereoselective and Stereospecific reactions