BPH-205: PHARMACEUTICS – V
(PHARMACEUTICAL ENGINEERING-I)
THEORY
Note: Examiner to set eight questions and the candidates are required to attempt any five.
1.Flow of fluids: Introduction, mechanism of fluid flow, Reynolds number and its Significance, Bernoulli's theorem, manometers and friction losses in pipes, measurement of flow rate using headmeters, displacement meters and dilution methods. Regulation of flow using valves, pumps and common problems like water hammer.(12)
2.Heat Transfer: Modes of heat transfer, Different laws of heat transfer, overall heat transfer coefficient, single pass heater, multipass heater, liquid-liquid heat interchanger/ exchanger and finned tubes heat exchangers.(6)
3.Evaporation: Principle, Factors affecting evaporation, natural circulation evaporators, forced circulation evaporators, film evaporators, multiple effect evaporation, material and energy balance of evaporators.(8)
4.Drying: Theory, definitions, behavior of solids during drying, static bed dryers, moving bed dryers, fluidizes bed dryer and pneumatic bed dryers. (3)
5.Centrifugation: theory, industrial centrifuges.(4)
6.Filtration: Theory, filter aids, filter media, industrial filters i.e. sand filter, filter
presses, rotary drum filter, leaf filters, edge filter. Ultrafiltration.(8)
7.Humidification, dehumidification and air conditioning: Definitions, Principles of Humidification, dehumidification and air conditioning, psychrometry, humidity measurement, large scale equipment for humidification and dehumidification, cooling towers. (5)
8.Refrigeration: Principle and equipments employed for vapor compression, steam jet and absorption types of refrigeration cycles, applications in Pharmacy.(4)
Books Recommended (Latest edition):
- McCabe and Smith, Unit Operations for Chemical Engineering, 6th edition, McGraw Hill, N.Y.
- G. Gunn and S.J. Carter and Gunn's Tutorial Pharmacy, Pitman Medical Publishing Co., London, 1972.
- L.A. Lachman, H.A. Liberman and J.L. Kanig, The Theory and Practice of Industrial Pharmacy, 3rd edition, Lea and Febiger, Philadelphia, U.S.A.
- Badger, Introduction to Chemical Engineering, McGraw Hill Co., International Student edition (Latest edition).
- E.A. Rowlins, Bentley's Text Book of Pharmaceutics, Bailliere Tindall and Cox, London (Latest Edition).
- K. Sambamurthy, Pharmaceutical Engineering, New Age Int. Publishers, New Delhi, 2003.